The increasing number of people living with two or more chronic disorders (multimorbidities) poses an urgent need to better understand underlying mechanisms for better prevention and care throughout the life course. Somatic disorders (e.g., type 2 diabetes) and brain disorders (e.g., Alzheimer’s disorder) often co-occur. This session aims to explore the link between mental and non-mental disorders and how to better address it in clinical practice and medical education.